PAPERS ARCHIVE

2011

  1. C. Taurino, L. Frattini, G.L. Marcone, L. Gastaldo, F. Marinelli (2011). Actinoplanes teichomyceticus ATCC 31121 as a cell factory for producing teicoplanin. Microb Cell Fact. 10: 82-94.
  2. F. Marinelli and G.L. Marcone (2011). Small Molecules: Microbial Secondary Metabolites. In: Comprehensive Biotechnology Second Edition; 3: 285–297. Murray Moo-Young Editor, Elsevier.

 2010

  1. S. JOVETIC, Y. ZHU, G.L. MARCONE, F. MARINELLI, J. TRAMPER (2010). β-Lactam and glycopeptide antibiotics: first and last line of defense? TRENDS BIOTECHNOL. 28: 596-604.
  2. F. MARINELLI, A. TOMASZ (2010). Antimicrobials. CURR OPIN MICROBIOL. 13: 547-550.
  3. G.L. MARCONE, L. FOULSTON, E. BINDA, F. MARINELLI, M. BIBB, F. BELTRAMETTI (2010). Methods for the genetic manipulation of Nonomuraea sp. ATCC 39727. J IND MICROBIOL BIOTECHNOL. 37: 1097-1103.
  4. F. VOLONTE, L. POLLEGIONI, G. MOLLA, L. FRATTINI, F. MARINELLI, L. PIUBELLI (2010). Production of recombinant cholesterol oxidase containing covalently bound FAD in Escherichia coli. BMC BIOTECHNOLOGY. 10: 33-42.
  5. G.L. MARCONE, F. BELTRAMETTI, E. BINDA, L. CARRANO, L. FOULSTON, A. HESKETH, M. BIBB, F. MARINELLI (2010) Novel mechanism of glycopeptide resistance in the A40926 producer Nonomuraea sp. ATCC 39727. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 54(6): 2465-2472.
  6. G.L. MARCONE, L. CARRANO, F. MARINELLI, F. BELTRAMETTI (2010). Protoplast preparation and reversion to the normal filamentous growth in antibiotic-producing uncommon actinomycetes. JOURNAL OF ANTIBIOTICS (Tokyo) 63(2):83-88.

2009

  1. M. Brunati, J.L. Rojas, F. Sponga, I. Ciciliato, D. Losi, E. Göttlich, S. de Hoog, O. Genilloud, F. Marinelli (2009). Diversity and pharmaceutical screening of fungi from benthic mats of Antarctic lakes. Marine Genomics, vol.2, pp.43-50.
  2. f. Marinelli(2009).Antibiotics and Streptomyces: the future of antibiotic discovery. Microbiology Today, vol.36, pp.20-23.
  3. F. MARINELLI (2009). Chapter 2. From microbial products to novel drugs that target a multitude of disease indications. METHODS IN ENZYMOLOGY, vol.458, pp.29-58.
  4. J.L. Rojas, J. Martín, J.R. Tormo, F. Vicente, M. Brunati, I. Ciciliato,, D. Losi, S. Van Trappen, J. Mergaert, J. Swings,F. Marinelli, O. Genilloud(2009).Bacterial diversity from benthic mats of Antarctic lakes as asource of new bioactive metabolites.Marine Genomics, vol.2, pp.33-41.
  5. D. ROMANO, G. MOLLA, L. POLLEGIONI, F. MARINELLI (2009). Optimization of human D-amino acid oxidase expression in Escherichia coli. PROTEIN EXPRESSION AND PURIFICATION 68(1): 72-78.

2008

  1. N. Biondi, M. Tredici, A. Taton, A. Wilmotte,D. Hodgson, D. Losi, F. Marinelli(2008).Cyanobacteria from benthic mats of Antarctic lakes as a source of new bioactivities, Journal of Applied Microbiology. vol.105, pp.105-115.
  2. F. Castiglione, A. Lazzarini, L. Carrano, E. Corti, I. Ciciliato, L. Gastaldo, P. Candiani, D. Losi, F. Marinelli,E. Selva, F. Parenti (2008). Determining the structure and mode of action of microbisporicin, a potent lantibiotic active against multiresistant pathogens. Chemistry & Biology. vol. 15, pp. 22-31.
  3. R. Gandolfi, R. Villa, S. Jovetic, F. Marinelli, F. Molinari (2008).Use of biocatalysis in pharmaceutical manufacturing. Bioforum Europe. vol. 12, pp. 10-12.
  4. S. JOVETIC, M. FEROGGIO, F. Marinelli, G. LANCINI (2008). Factors influencing cell fatty acid composition and A40926 antibiotic complex production in Nonomuraea sp. ATCC 39727. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY. vol. 35, pp. 1131-1138.
  5. F. Volontè, F. Marinelli, L. Gastaldo, S. Sacchi, M.S. Pilone, L. Pollegioni, G. Molla (2008).Optimization of glutaryl-7-aminocephalosporanic acid acylase expression in E. coli. Protein Expression AND Purification. vol.61, pp. 131-137.

2007

  1. F. BELTRAMETTI, A. CONSOLANDI, L. CARRANO, F. BAGATIN, R. ROSSI, L. LEONI, E. ZENNARO, E. SELVA, F. MARINELLI (2007). Resistance to glycopeptide antibiotics in the teicoplanin producer is mediated by van-gene homologue expression directing the synthesis of a modified cell wall peptidoglycan. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. vol. 51, pp. 1135-1141.
  2. F. BELTRAMETTI, D. BARUCCO, R. ROSSI, E. SELVA, F. MARINELLI (2007). Protoplast fusion and gene recombination in the uncommon actinomycete Planobispora rosea producing GE2270. JOURNAL OF ANTIBIOTICS. vol. 60, pp. 447-454.
  3. A. BOSELLI, E. ROSINI, G.L. MARCONE, S. SACCHI, L. MOTTERAN, M.S. PILONE, L. POLLEGIONI. (2007). Glycine oxidase from Bacillus subtilis: Role of Histidine 244 and Methionine 261. BIOCHIMIE. vol. 89, pp. 1372-1380.
  4. F. CASTIGLIONE, L. CAVALETTI, D. LOSI, A. LAZZARINI, L. CARRANO, M. FEROGGIO, I. CICILIATO, E. CORTI, G. CANDIANI, F. MARINELLI, E. SELVA. (2007). A novel lantibiotic acting on bacterial cell wall synthesis produced by the uncommon actinomycete Planomonospora sp. BIOCHEMISTRY. vol. 46, pp. 5884-5895.
  5. R. GANDOLFI, S. JOVETIC, F. MARINELLI, F. MOLINARI. (2007). Biotransformations of lipoglycopeptides to obtain novel antibiotics. JOURNAL OF ANTIBIOTICS. vol. 60, pp. 265-271.
  6. S. DI PALO, R. GANDOLFI, S. JOVETIC, F. MARINELLI, D. ROMANO, F. MOLINARI. (2007). A new bacterial mannosidase for the selective modification of ramoplanin and its derivatives. ENZYME AND MICROBIAL TECHNOLOGY. vol. 41, pp. 806-811.
  7. M.S. PILONE, A. BOSELLI, E. ROSINI, G.L. MARCONE, V. JOB, L. POLLEGIONI, G. MOLLA. (2007). Glycine oxidase from Bacillus subtilis: role of histidine 244 and methionine 261. ITALIAN JOURNAL OF BIOCHEMISTRY. vol. 56, pp. 113.

2006

  1. A. TATON, S. GRUBISIC, D. ERTZ, D. A. HODGSON, R. PICCARDI, N. BIONDI, M. TREDICI, M. MAININI, D. LOSI, F. MARINELLI, A. WILMOTTE. (2006). Polyphasic study of Antarctic cyanobacterial strains. JOURNAL OF PHYCOLOGY. vol. 42, pp. 1257-1270.
  2. F. BELTRAMETTI, R. ROSSI, E. SELVA, F. MARINELLI. (2006). Antibiotic production improvement in the rare actinomycete Planobsipora rosea by selection of resistance mutations to the aminoglycosides streptomycin and gentamycin and to rifamycin. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY. vol. 33, pp. 283-288.
  3. L. BRANDI, A. LAZZARINI, L. CAVALETTI, M. ABBONDI, E. CORTI, I. CICILIATO, L. GASTALDO, A. MARAZZI, M. FEROGGIO, A. FABBRETTI, A. MAIO, L. COLOMBO, S. DONADIO, MARINELLI F., D. LOSI, C. O. GUALERZI, E. SELVA. (2006). Novel tetrapeptide inhibitors of bacterial protein synthesis produced by a Streptomyces sp. BIOCHEMISTRY. vol. 45, pp. 3700-3710.
  4. S. JOVETIC, F. MARINELLI, J. TRAMPER. (2006). Continuous biotransformation of glycopeptide antibiotic A40926 in a cascade of three airlift bioreactors using immobilized Actinoplanes teichomyceticus cells. ENZYME AND MICROBIAL TECHNOLOGY. vol. 38, pp. 34-39.
  5. G. MOLLA, E. ROSINI, G.L. MARCONE, S. LORENZI, M.S. PILONE, L. POLLEGIONI. (2006). Techniques for the engineering of D-Amino Acid Oxidase substrate specificity. In: R. KONNO et al. EDITORS. D-AMINO ACIDS: A NEW FRONTIER IN AMINO ACID AND PROTEIN RESEARCH – PRACTICAL METHODS AND PROTOCOLS. (vol. Chapter 6.9, pp. 491-501). New York: Nova Science Publishers, Inc. (UNITED STATES).

2005

  1. F. GASPARI, Y. PAITAN, M. MAININI, D. LOSI, E. Z. RON, F. MARINELLI (2005). Myxobacteria isolated in Israel as potential source of new anti-infectives. JOURNAL OF APPLIED MICROBIOLOGY. vol. 98, pp. 429-439.
  2. F. MOLINARI, D. ROMANO, R. GANDOLFI, R.M. KROPPENSTEDT, F. MARINELLI (2005). Newly isolated Streptomyces spp. as enantioselective biocatalysts: hydrolysis of 1,2-O-isopropylidene glycerol racemic esters. JOURNAL OF APPLIED MICROBIOLOGY. vol. 99, pp. 960-967.
  3. M. BRUNATI, A. BAVA, F. MARINELLI, G. LANCINI. (2005). Influence of leucine and valine on ramoplanin production by Actinoplanes sp. ATCC 33076. JOURNAL OF ANTIBIOTICS. vol. 58, pp. 473-478.
  4. A. LAZZARINI, L. GASTALDO, P. CANDIANI, I. CICILIATO, D. LOSI, F. MARINELLI, E. SELVA, F. PARENTI. (2005). Antibiotics 107,891, its factor A1 and A2, pharmaceutically acceptable salts and compositions, and use thereof. World-wide Patent WO 2005/014628.
  5. M.S. PILONE, L. MOTTERAN, G. MOLLA, G.L. MARCONE, L. POLLEGIONI. (2005). The metabolic role of glycine oxidase from Bacillus subtilis: new insights. In: T. NISHINO et al. EDITORS. FLAVINS AND FLAVOPROTEINS. (pp. 767-772). Tokyo: Architect, Inc. (JAPAN).
  6. M.S. PILONE, L. MOTTERAN, G. MOLLA, G.L. MARCONE, L. POLLEGIONI. (2005). The metabolic role of glycine oxidase from Bacillus subtilis: new insights. In: T. NISHINO ET AL EDITORS. FLAVINS AND FLAVOPROTEINS. (pp. 767-772). : ARCHITECT INC.

2004

  1. I. CICILIATO, E. CORTI, E. SARUBBI, S. STEFANELLI, L. GASTALDO, N. MONTANINI, M. KURZ, D. LOSI, F. MARINELLI, E. SELVA. (2004). Antibiotics GE23077, novel inhibitors of bacterial RNA polymerase I. Taxonomy, Isolation and Characterization. JOURNAL OF ANTIBIOTICS. vol. 57, pp. 210-217.
  2. M. BRUNATI, F. MARINELLI, C. BERTOLINI, R. GANDOLFI, D. DAFFONCHIO, F. MOLINARI. (2004). Biotransformations of cinnamic and ferulic acid with actinomycetes. ENZYME AND MICROBIAL TECHNOLOGY. vol. 34, pp. 3-9.
  3. F. BELTRAMETTI, S. JOVETIC, M. FEROGGIO, L. GASTALDO, E. SELVA, F. MARINELLI. (2004). Valine influences production and complex composition of glycopeptide antibiotic A40926 in fermentation of Nonomuraea sp. ATCC 39727. JOURNAL OF ANTIBIOTICS. vol. 57, pp. 37-44.
  4. F. MARINELLI, M. BRUNATI, F. SPONGA, I. CICILIATO, D. LOSI, S. VAN TRAPPEN, J. MERGAERT, J. SWINGS, E. GTTLICH, G.S. DE HOOG, J.L. ROJAS, O. GENILLOUD. (2004). Biotechnological exploitation of heterotrophic bacteria and filamentous fungi isolated from benthic mats of antarctic lakes. In: I. KURTBKE AND J.SWINGS. MICROBIAL GENETIC RESOURCES AND BIODISCOVERY. (pp. 163-184). Queensland: Queeslasnd Complete Printing Services. (AUSTRALIA).
  5. D. LOSI, L. CAVALETTI, A. LAZZARINI, P. CANDIANI, F. CASTIGLIONE, F. MARINELLI. (2004). Antibiotics ID 97518, pharmaceutically acceptable salts and compositions, and use thereof. EUROPEAN PATENT 1481986A1.

2003

  1. F. BELTRAMETTI, A. LAZZARINI, C. BRUNATI, A. MARAZZI, S. JOVETIC, E. SELVA, F. MARINELLI. (2003). Production and characterization of monochlorinated and dechlorinated A40926 derivatives. JOURNAL OF ANTIBIOTICS. vol. 56, pp. 773-782.
  2. F. BELTRAMETTI, A. LAZZARINI, C. BRUNATI, E. SELVA, F. MARINELLI. (2003). Production of demannosyl-A40926 by a Nonomurea sp. ATCC 39727 mutant strain. JOURNAL OF ANTIBIOTICS. vol. 56, pp. 310-313.
  3. L. GASTALDO, F. MARINELLI. (2003). Changes in GE2270 antibiotic production in Planobispora rosea through modulation of methylation metabolism. MICROBIOLOGY. vol. 149, pp. 1523-1532.
  4. M.J. BUTLER, E. TAKANO, P. BRUHEIM, S. JOVETIC, F. MARINELLI, M.J. BIBB. (2003). Deletion of scbA enhances antibiotic production in Streptomyces lividans 132. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. vol. 61, pp. 512-516.
  5. S. JOVETIC, L. DE BRESSER, J. TRAMPER, F. MARINELLI. (2003). Deacylation of antibiotic A40926 by immobilized Actinoplanes teichomyceticus cells in an internal-loop-air-lift bioreactor. ENZYME AND MICROBIAL TECHNOLOGY. vol. 32, pp. 546-552.
  6. E. SELVA, F. MARINELLI, D. LOSI, L. CAVALETTI, A. LAZZARINI, A. MARAZZI. (2003). Antibiotics GE 81112 factors A, B, B1, pharmaceutically accepatble salts and compositions, and use thereof. World-wide Patent WO 03/046192.
  7. I. CICILIATO, E. CORTI, E. SARUBBI, S. STEFANELLI, N. MONTANINI, F. MARINELLI, M. KURZ, E. SELVA. (2003). Antibiotics GE 23077, pharmaceutically acceptable salts and compositions, and use thereof. US PATENT NO 6,586,393.

2002

  1. M.J. BUTLER, P. BRUHEIM, S. JOVETIC, F. MARINELLI, P.W. POSTA, M.J. BIBB. (2002). Engineering of primary carbon metabolism for improved antibiotic production in Streptomyces lividans. APPLIED AND ENVIRONMENTAL MICROBIOLOGY. vol. 68, pp. 4731-4739.
  2. V. JOB, G.L. MARCONE, M.S. PILONE, L. POLLEGIONI. (2002). Glycine oxidase from Bacillus subtilis – Characterization of a new flavoprotein. THE JOURNAL OF BIOLOGICAL CHEMISTRY. vol. 277, pp. 6985-6993.
  3. M.S. PILONE, L. MOTTERAN, G.L. MARCONE, G. MOLLA, V. JOB, L. POLLEGIONI. (2002). Reaction mechansim of glycine oxidase, a new flavoenzyme active on glycine. ITALIAN JOURNAL OF BIOCHEMISTRY. vol. 51, pp. 116.
  4. L. MOTTERAN, G.L. MARCONE, G. MOLLA, V. JOB, M.S. PILONE, L. POLLEGIONI. (2002). Characterization of the new flavoprotein Glycine Oxidase from Bacillus subtilis. In: S. CHAPMAN ET AL. EDITORS. FLAVINS AND FLAVOPROTEINS. (pp. 1015-1020). Cambridge: R. Weber Agency for Scientific Publications (UNITED KINGDOM).

2001

  1. S. JOVETIC, H.H. BEEFTINK, J. TRAMPER, F. MARINELLI. (2001). Diffusion of (de)acylated antibiotic A40926 in alginate and carrageenan beads with or without cells and /or soybean meal. ENZYME AND MICROBIAL TECHNOLOGY. vol. 28, pp. 510-514.

2000

  1. A. LAZZARINI, L. CAVALETTI, G. TOPPO, F. MARINELLI. (2000). Rare genera of actinomycetes as potential producers of new antibiotics. ANTONIE VAN LEEUWENHOEK. vol. 73, pp. 399-405.
  2. R. GANDOLFI, F. MARINELLI, A. LAZZARINI, F. MOLINARI. (2000). Cell-bound and extracellular carboxylesterases from Streptomyces: hydrolytic and synthetic activities. JOURNAL OF APPLIED MICROBIOLOGY. vol. 89, pp. 870-875.

SEZIONE DI SCIENZE E TECNOLOGIE BIOLOGICHE – DBSV